Lupus and Pulmonary Nodules Consistent With Bronchiolitis Obliterans Organizing Pneumonia Induced by Carbamazepine
December 1997
in “
Mayo Clinic proceedings
”
Studysummary This report describes a case where a woman developed bronchiolitis obliterans organizing pneumonia and lupus potentially induced by carbamazepine, a reaction not previously documented. Our plain-language summary of this paper — not a Tressless recommendation.
A 52-year-old woman taking carbamazepine for epilepsy developed facial erythema, arthralgia, dyspnea, and multiple pulmonary nodules, which were diagnosed as bronchiolitis obliterans organizing pneumonia (BOOP). High levels of antinuclear and antihistone antibodies indicated carbamazepine-induced lupus (CIL). Her symptoms resolved after discontinuing carbamazepine without the need for anti-inflammatory drugs, underscoring the importance of considering drug-induced causes in patients with new respiratory symptoms during carbamazepine treatment.
