April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” A specific mutation in the TRPV3 gene causes hair follicle cells to develop improperly, leading to hair loss.
43 citations
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April 2010 in “Developmental Biology” 122 citations
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July 1994 in “Journal of Investigative Dermatology”
94 citations
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February 1994 in “The journal of investigative dermatology/Journal of investigative dermatology” EGF makes hair follicles grow longer but stops hair production.
59 citations
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August 1981 in “PubMed” The study described trichilemmal keratinization as a distinct type of keratinization in the hair follicle, characterized by the conversion of the outer root sheath's stratified epithelium into anuclear keratin without a keratohyalin layer. This process was observed in the anagen phase below the sebaceous duct opening and in the catagen phase within the trichilemmal sac. The research, using electron microscopy on dog hairs, revealed complex infoldings of cells and unique ladder-like membrane coating granules in anagen, which were acid phosphatase-positive and potentially involved in the disintegration of the inner root sheath.