A Pilot Iron Substitution Program in Female Blood Donors With Iron Deficiency Without Anemia

    November 2010 in “ Vox Sanguinis ”
    C. Pittori, Andreas Buser, Urs Gasser, J. Sigle, Shabahang Job, Morven Rüesch, André Tichelli, Laura Infanti
    TLDR Iron supplements helped female blood donors with low iron avoid anaemia and return to donate again.
    The study conducted a pilot iron substitution program for premenopausal female blood donors with iron deficiency but without anemia. It involved 116 women aged ≤50 with adequate hemoglobin levels and serum ferritin ≤10 ng/ml, who were offered iron supplementation for 16 weeks. The program aimed to prevent anemia and improve donor retention. Results showed a significant increase in serum ferritin levels (from 7.12 to 25.2 ng/ml) and resolution of symptoms such as fatigue, sleep disturbances, and hair loss. No cases of anemia were reported, and 60% of participants completed the program and donated blood again. The study concluded that targeted iron supplementation effectively prevented anemia and enhanced donor return rates.
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