Investigation of Bisphenol A and Phthalate Levels in Idiopathic Hyperandrogenemia

This study investigated the relationship between Bisphenol A (BPA) and mono-ethylhexyl phthalate (MEHP) levels in women with idiopathic hyperandrogenemia, a condition characterized by hirsutism and elevated androgen levels. The study included 91 women aged 18-45, with 43 in the patient group and 48 in the control group. Results showed that urinary BPA levels were significantly higher in the patient group compared to the control group (1.6 ng/ml vs. 0.55 ng/ml, p=0.035), suggesting a potential role of BPA in idiopathic hyperandrogenemia. Conversely, MEHP levels were higher in the control group (1.81 ng/ml vs. 1.66 ng/ml, p=0.01), indicating the need for further research on phthalate metabolites. The study highlights the importance of examining endocrine-disrupting chemicals in the etiology of hyperandrogenemia.