Effect of Interferon Therapy on Quality of Life in Patients with Chronic Hepatitis B

    January 2024 in “ Scientific Reports ”
    Mengdi Zhang, Meijuan Wan, Wen Wang, Shumei Lin, Xi Zhang
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    Studysummary In this study, researchers examined chronic hepatitis B patients and found that those undergoing interferon therapy reported higher quality of life than those on non-antiviral or nucleoside/nucleotide analogue treatments, despite potential side effects.
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    A study involving 287 chronic hepatitis B patients compared the quality of life among those receiving interferon therapy, nucleoside/nucleotide analogues, and non-antiviral treatment. Despite potential side effects and costs, interferon therapy was associated with a higher quality of life compared to the other treatments (p < 0.05). Factors such as resilience, presenteeism, hair loss, and antiviral treatment influenced quality of life (p < 0.05). The findings suggest that interferon therapy does not negatively impact daily life and work for CHB patients.
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