Inositol and FSH: A new frontier for the androgenetic alopecia treatment

In 2015, a longitudinal observational study was conducted on 10 to 30 patients with androgenetic alopecia (AA) to evaluate the therapeutic effect of insulin-sensitizing integration. The patients were treated with different doses of inositol and folic acid based on their BMI. The results, recorded at three and six months of treatment, showed a significant reduction in BMI/HC, PCOS, and cutaneous hyperandrogenism signs. The treatment also resulted in a 20-70% reduction in hair loss without side effects. These findings supported the hypothesis about inositol acting as a second FSH messenger and demonstrated a reduction in androgen and their peripheral effects. However, the study concluded that further double-blind randomized studies were needed to validate the administration of inositol definitively.