Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis
August 2013
in “
Experimental Dermatology
”
Research cited in this study
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research Polyamines and Hair: A Couple in Search of Perfection
Polyamines are important for hair growth, but more research is needed to understand their functions and treatment potential.
research A Novel Mutation in Hr Causes Abnormal Hair Follicle Morphogenesis in Hairpoor Mouse, an Animal Model for Marie Unna Hereditary Hypotrichosis
A new mutation in the Hr gene causes hair loss in mice, similar to a human hair disorder.
research Exogen, Shedding Phase of the Hair Growth Cycle: Characterization of a Mouse Model
Researchers found that hair shedding happens mostly when new hair is growing and involves a unique process.
research Relation of Skin Polyamines to the Hairless Phenotype in Transgenic Mice Overexpressing Spermidine/Spermine N1-Acetyltransferase
research Ornithine Decarboxylase Transgenic Mice as a Model for Human Atrichia with Papular Lesions
ODC transgenic mice can model human hair loss with skin lesions.
research Dynamic expression of ornithine decarboxylase in hair growth
research Activation of Polyamine Catabolism Profoundly Alters Tissue Polyamine Pools and Affects Hair Growth and Female Fertility in Transgenic Mice Overexpressing Spermidine/SpermineN 1-Acetyltransferase
research Ornithine decarboxylase overexpression is a sufficient condition for tumor promotion in mouse skin.
research Modulation of Murine Hair Follicle Function by Alterations in Ornithine Decarboxylase Activity
research The Character 'Hairless' in the Mouse
Hairless mice lack fur due to a genetic mutation affecting skin response, not hormone issues.