Hair Trace Elements in Children With Autism Spectrum Disorders: Systematic Literature Review
February 2021
Studysummary This review discusses the association between hair element levels and autism spectrum disorder, reporting links between neurotoxic elements like mercury and lead and pathogenesis, alongside potentially protective roles for zinc and copper balance.
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The systematic literature review aimed to explore the relationship between hair trace elements and autism spectrum disorder (ASD). The review found that the pathogenesis of ASD was associated with exposure to toxic elements like mercury (Hg) and lead (Pb), which act as neurotoxicants. Additionally, the study highlighted the significance of the zinc to copper (Zn/Cu) ratio, suggesting that higher levels of zinc and lower levels of copper may have a protective role against ASD. However, due to varied methodologies and sample sizes in the studies reviewed, direct comparisons of results were not informative.