Hair Loss: Pathogenesis And Prevention: A Literature Review

    May 2025 in “ Quality in Sport
    Teresa Sowińska, Mikołaj Łabuda, Aleksandra Słojewska, Agata Kotkowiak, Oliwia Mentel, Adrianna Bogucka, Agnieszka Szema, Klaudia Królikowska, Jakub Sikora, Karolina Knychalska
    TLDR Hair loss is caused by genetics, hormones, stress, and environment, and can be managed with good nutrition, stress control, and treatments.
    Hair loss, or alopecia, is influenced by genetic, hormonal, immune, and environmental factors, with significant psychosocial impacts. Disruptions in the hair growth cycle, often due to hormonal changes and stress, are central to hair loss. Androgens, cortisol, and thyroid hormones are crucial, while immune responses and environmental factors also contribute. Preventive strategies include balanced nutrition, stress management, and topical treatments. Understanding these mechanisms aids in better diagnosis and personalized treatment plans for those affected by hair loss.
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      community How does hair loss and recovery work?

      in Chat  12 upvotes 8 months ago
      Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

      community C’est terrible - at my wits end

      in Female  450 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community Quit vaping/smoking = 80% less loss

      in Research/Science  235 upvotes 1 year ago
      Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

      community Spironolactone for 11 years, finasteride for almost 5 years, started oral minoxidil in November 😢 ended oral contraceptive in Dec.

      in Progress Pictures  224 upvotes 1 year ago
      A user shared their 11-year experience with spironolactone and nearly 5 years with finasteride for hair loss, recently adding oral minoxidil and stopping birth control. Various treatments were discussed, including organic options, checking for underlying health issues, considering dutasteride, and the potential role of progesterone in hair loss.

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