Hair loss is an important symptom of the menopause

    January 2018 in “BMJ
    Amr Salam, Christos Tziotzios, David A. Fenton
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    TLDR Many women experience significant hair loss during menopause, and topical minoxidil is an effective treatment.
    The document highlights that hair loss, specifically female pattern hair loss (FPHL), is a significant symptom experienced by many women around menopause. FPHL, also known as androgenetic alopecia, is the most common cause of hair loss in women and typically presents with progressive thinning at the top of the scalp while the frontal hairline remains intact. It often begins at or after menopause and can cause considerable psychological distress, including symptoms of depression and anxiety. The role of androgens in FPHL is less clear than in male pattern hair loss, as most women with FPHL do not show signs of hyperandrogenism. The document emphasizes the effectiveness of topical minoxidil as a non-hormonal treatment for FPHL, which is available in 2% and 5% preparations. While the exact mechanism of action is unknown, its efficacy in promoting hair regrowth is supported by a systematic review and meta-analysis of randomized controlled trials. Patients are advised to use minoxidil for at least 12 months before assessing its effectiveness, as results may not be apparent in the first four months.
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