Finasteride: Not Guilty After All?

    October 2006 in “ The Lancet Oncology
    Tabitha M. Powledge
    TLDR Finasteride reduces prostate cancer risk but may increase aggressive cancer risk slightly.
    The 2003 trial of the 5α-reductase inhibitor finasteride demonstrated a nearly 25% reduction in prostate cancer risk compared to a placebo. However, this benefit was overshadowed by a 1.3% increase in the incidence of aggressive, high-grade prostate cancer among users. These mixed results led to a tempered enthusiasm for the drug despite its potential in reducing overall prostate cancer risk.
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