The Role of Family History and Its Influence on the Onset Time in Female Pattern Hair Loss

January 2020 in “ Postepy Dermatologii I Alergologii ”

Adam Łukasik, Karolina Kozicka, Agata Kłosowicz, Andrzej Jaworek, Anna Wojas-Pelc

female pattern hair loss FPHL genetic origins family history hair thinning female pattern baldness genetic hair loss

TLDR Family history, especially on the mother's side, increases the risk of female pattern hair loss.

The study investigated the genetic origins of female pattern hair loss (FPHL) in 111 women with FPHL and 129 women without hair thinning from the Polish population. Results showed that 62.2% of FPHL patients had a positive family history of hair loss, compared to only 3.1% in the healthy group. A significant correlation was found between FPHL and a positive family history on the mother’s side. Additionally, hair loss in grandparents was three times more frequent in patients with disease onset before age 40. The findings suggested that a positive family history, especially on the mother’s side and involving multiple family members, may indicate a higher risk of developing FPHL.

View this study on termedia.pl →

Discuss this study in the Community →

Research cited in this study

10 / 10 results

Correlation Between Clinical Features, Biochemical Parameters, and Histopathological Findings in Women with Patterned Baldness: A Study from North India

research Correlation Between Clinical Features, Biochemical Parameters, and Histopathological Findings in Women with Patterned Baldness: A Study from North India

4 citations, January 2019 in “PubMed”

Patterned hair loss in women is linked to hormonal imbalances and biochemical changes, and should be evaluated for underlying health issues.

Frequency, Severity, and Related Factors of Androgenetic Alopecia in Dermatology Outpatient Clinic: Hospital-Based Cross-Sectional Study in Turkey

research Frequency, Severity, and Related Factors of Androgenetic Alopecia in Dermatology Outpatient Clinic: Hospital-Based Cross-Sectional Study in Turkey

37 citations, February 2017 in “Anais Brasileiros De Dermatologia”

AGA more common in men, increases with age, linked to family history, hypertension, dyslipidemia, and smoking.

research Female Pattern Hair Loss: A Retrospective Study in a Tertiary Referral Center

14 citations, January 2016 in “International Journal of Trichology”

Many women with hair loss also have thyroid issues, high blood pressure, and low Vitamin D.

research Factors Associated With Female Pattern Hair Loss And Its Prevalence In Taiwanese Women: A Community-Based Survey

33 citations, November 2012 in “Journal of The American Academy of Dermatology”

FPHL common in Taiwanese women; risk factors include BMI, high glucose, early puberty, fewer childbirths, oral contraceptives, and UV exposure.

research Prevalence of Androgenetic Alopecia in China: A Community-Based Study in Six Cities

126 citations, January 2010 in “British Journal of Dermatology”

Baldness is more common in Chinese men than women, increasing with age, and is influenced by genetics.

research Prevalence of Male and Female Pattern Hair Loss in Maryborough

193 citations, August 2005 in “Journal of Investigative Dermatology Symposium Proceedings”

Hair loss common in Australia; men affected earlier, more often than Asians; women less concerned.

research Family History and Risk of Hair Loss

49 citations, January 2004 in “Dermatology”

Men with a family history of hair loss are more likely to experience it themselves, especially if both parents have hair loss.

research The Prevalence and Types of Androgenetic Alopecia in Korean Men and Women

157 citations, July 2001 in “British Journal of Dermatology”

AGA more common in men, Koreans have lower rates and unique patterns.

research Hair Density, Hair Diameter, and the Prevalence of Female Pattern Hair Loss

234 citations, February 2001 in “British Journal of Dermatology”

FPHL affects hair density and diameter, causing visible hair loss in older women.

research Incidence of Female Androgenetic Alopecia (Female Pattern Alopecia)

89 citations, January 2001 in “Dermatologic Surgery”

Hair loss in women is common, starts in late 20s, and affects 30% of women over 50.

Related Community Posts Join

6 / 1000+ results

community Spironolactine Update: 2 months (34, Female)

in Female 20 upvotes 7 years ago

A female user's experience using Spironolactone to treat Female Pattern Hair Loss (FPHL) and Androgenic Alopecia, as well as discussing the effectiveness of the drug at different dosages.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community One+ year 1mg Fin, Ketoconazole, and 3.75 Oral Min. I have DUPA. Switched from Topical to Oral Min.

in Progress Pictures 142 upvotes 2 years ago

A user's experience with hair loss treatments such as finasteride, ketoconazole, and oral minoxidil that have not yielded any results; other users suggest shaving the head or getting a wig, while others offer additional advice such as seeing a dermatologist, checking thyroid levels, switching to dutasteride and adding needling, and trying stemoxydine.

community Diagnosed with female pattern hair loss as a male with recent aggressive loss. Preemptively mourning the only part of myself I’ve ever come close to loving. Lost all motivation to do anything with my life.

in Progress Pictures 271 upvotes 1 year ago

The conclusion of the conversation is that the user should consider using treatments such as finasteride, minoxidil, and RU58841 to potentially reverse their hair loss. Other suggestions include using hair loss concealers and maintaining a healthy diet.

community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 2 years ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community Better then Minoxidil( at least for me and my family)

in Treatment 42 upvotes 10 months ago

Capronium Chloride and Trichoxidil are suggested as better alternatives to Minoxidil for hair growth without heart side effects. The Japanese Dermatological Association recommends topical Minoxidil over Capronium Chloride.

Related Research

1 / 1 results

research Androgenetic Alopecia in Adolescents

12 citations, February 2003 in “PubMed”