The Role of Family History and Its Influence on the Onset Time in Female Pattern Hair Loss

January 2020 in “ Postepy Dermatologii I Alergologii ”

Adam Łukasik, Karolina Kozicka, Agata Kłosowicz, Andrzej Jaworek, Anna Wojas-Pelc

female pattern hair loss FPHL genetic origins family history hair thinning female pattern baldness genetic hair loss

Studysummary This study found that a positive family history, especially from the mother's side and including grandparents, is associated with an increased risk of early-onset female pattern hair loss in Polish women. Our plain-language summary of this paper — not a Tressless recommendation.

The study investigated the genetic origins of female pattern hair loss (FPHL) in 111 women with FPHL and 129 women without hair thinning from the Polish population. Results showed that 62.2% of FPHL patients had a positive family history of hair loss, compared to only 3.1% in the healthy group. A significant correlation was found between FPHL and a positive family history on the mother’s side. Additionally, hair loss in grandparents was three times more frequent in patients with disease onset before age 40. The findings suggested that a positive family history, especially on the mother’s side and involving multiple family members, may indicate a higher risk of developing FPHL.

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