Familial Androgenetic Alopecia in Siblings with Normal Endocrinological Status

    July 2012 in “ Pediatric Dermatology
    A. Vozza, Andrea Bassi, Teresa Russo, G. Vozza
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    TLDR Two young siblings experienced hair loss without hormone issues or other skin problems.
    This document reports two cases of androgenetic alopecia (AGA) in two siblings, aged 6 and 8, whose mother had the same condition, without any association with other skin diseases or abnormalities in endocrinologic examinations. AGA is the most common type of hair loss in adults, but it has been rarely reported in children. The disease usually starts after puberty, but it has rarely been reported in prepubertal children. The diagnosis of AGA was made with clinical and dermoscopic parameters, so biopsy was not necessary. Hair loss patterns were categorized using the Ludwig classification, and the girls both showed a sparing of the frontal hairline, with only diffuse hair loss on the mid-frontal and parietal scalp, indicating Ludwig type I. No other associated cutaneous diseases were observed such as acne vulgaris, seborrheic dermatitis, or atopic dermatitis, and they had normal secondary sexual characteristics.
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