Epidermal field carcinogenesis in bald-headed: An attempt at finetuning early non-invasive detection

The study investigated the concept of field cancerization on the balding scalp, focusing on actinic changes due to photoaging. Using ultraviolet light-enhanced visualization, 50 healthy men over 50 years old with long-term baldness were examined for epidermal changes. The study identified faint mosaic melanoderma (FMM) and atypical scaliness on the scalp, which were not present on the forehead. These changes, distinct from common scalp conditions, suggested a potential link to actinic field carcinogenesis and early keratinocyte dysplasia, highlighting the need for early non-invasive detection methods in bald-headed individuals.