A Preliminary Study on the Relationship Between Environmental Endocrine Disruptors and Precocious Puberty in Girls

This preliminary study investigated the relationship between environmental endocrine disruptors and precocious puberty in girls, involving 30 girls with precocious puberty and 46 age- and race-matched prepubertal females. The study found that urinary levels of bisphenol A, monobutyl phthalate, and monomethyl phthalate were significantly higher in girls with precocious puberty, while blood levels of certain steroid hormones were lower compared to the prepubertal group. The results confirmed an association between phthalate exposure and the incidence of precocious puberty, suggesting that reducing children's exposure to phthalate esters should be a health priority.