A Preliminary Study on the Relationship Between Environmental Endocrine Disruptors and Precocious Puberty in Girls

    Fang Zhou, Zhenzhen Jin, Li Zhu, Fang Huang, Angzhi Ye, Chunguang Hou
    TLDR Reducing phthalate exposure may help prevent early puberty in girls.
    This preliminary study examined the relationship between environmental endocrine disruptors (EDCs) and precocious puberty (PP) in girls by comparing 30 girls with PP to 46 prepubertal girls. It found that urinary levels of bisphenol A, monobutyl phthalate, and monomethyl phthalate were significantly higher in the PP group, while certain steroid hormone levels were lower. These findings suggested a link between phthalate exposure and PP, emphasizing the importance of reducing children's exposure to phthalate esters. The study also noted the need for larger sample sizes and long-term follow-up to better understand EDCs' impact on children's health.
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