The Patient Outcomes With EGFR-Mutated Advanced Non-Small-Cell Lung Cancer Receiving Aumolertinib As First-Line Treatment

    June 2024 in “ Journal of Clinical Oncology ”
    Jisheng Li, Zhao Wen, Hongxin Li, Tiantian Xuan, Chengjun Wang, Rongyu Zhang, Chuang Yang, Jian Wang, Cuihua Yi
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    TLDR Aumolertinib is effective and well-tolerated for treating advanced lung cancer with EGFR mutations.
    A study involving 33 patients with advanced non-small cell lung cancer (NSCLC) treated with aumolertinib as a first-line therapy showed promising results. The objective response rate (ORR) was 65.2%, and the disease control rate (DCR) was 91.3%. Patients experienced improvements in general health status, functional status, and key symptoms such as cough, sore mouth or tongue, and various types of pain. These findings align with the results of the AENEAS trial, indicating that aumolertinib is effective and well-tolerated in treating EGFR-mutated advanced NSCLC.
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