Efficacy of Platelet-Rich Plasma in Non-Surgical Aesthetic Procedures: Systematic Review and Meta-Analysis

This systematic review and meta-analysis evaluated the efficacy and safety of platelet-rich plasma (PRP) in non-surgical aesthetic procedures, focusing on facial rejuvenation and alopecia. Four randomized controlled trials were included, demonstrating that PRP significantly improved hair density (mean difference: 26.4 ± 6.2 units/cm²) and facial texture by up to 35%. The standardized mean difference was 1.17 (95% CI: 0.51-1.84; p < 0.001), indicating a strong effect. No serious adverse events were reported. The study concludes that PRP is an effective and safe option for treating androgenetic alopecia and facial rejuvenation, recommending standardization of protocols and long-term follow-up studies.