Efficacy of Ozonated Olive Oil as a Topical Treatment for Dermatophytosis Caused by T. Mentagrophytes in Rat Model

    January 2025 in “ Letters in Drug Design & Discovery ”
    Ali Mohaghegh, M. El Mansouri, Leila Etemad, Vahid Soheili, Atoosa Haghighzadeh, Saba Dadpour, Omid Rajabi
    TLDR Ozonated olive oil may effectively treat fungal skin infections.
    The study investigated the antifungal effects of ozonated olive oil as a topical treatment for dermatophytosis caused by Trichophyton mentagrophytes in a rat model. Thirty male Wistar albino rats were treated with different concentrations of ozonated olive oil and compared to terbinafine. Results showed that ozonated olive oil had a minimum inhibitory concentration (MIC) of 2.5 μg/mL, demonstrating significant antifungal effects by reducing inflammation and promoting hair growth, similar to the effects of terbinafine. The study concludes that ozonated olive oil may be a viable alternative treatment for Trichophyton infections.
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