Efficacy and Safety of Low-Dose Oral Minoxidil in Men with Androgenic Alopecia

December 2020 in “ Dermatología argentina ”

Federico Pastore

minoxidil oral minoxidil androgenic alopecia topical minoxidil finasteride Rogaine Propecia

TLDR Low-dose oral minoxidil effectively treats male pattern baldness.

The study "Eficacia y seguridad del minoxidil oral a bajas dosis en hombres con alopecia androgénica" conducted by Federico Pastore involved 32 male patients aged 18 to 45 years with androgenic alopecia. The patients were treated with a daily dose of 1.25 mg of oral minoxidil for 24 weeks. Of these patients, 18 (56.2%) had never received treatment, while 14 (43.8%) had previously failed treatment with 5% topical minoxidil twice a day or oral finasteride for at least 1.5 to 2 years.

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Research cited in this study

1 / 1 results

research Efficacy and Safety of Very-Low-Dose Oral Minoxidil 1.25 mg in Male Androgenetic Alopecia

19 citations, May 2020 in “Journal of The American Academy of Dermatology”

Low-dose oral minoxidil improves hair growth in male hair loss.

Related Community Posts Join

6 / 1000+ results

community ~5 months topical minoxidil + oral finasteride results (swipe images). Slacked with minoxidil this past month, trying to wean off anyways. My last update because I’m hopping off fin and switching to RU in a few weeks (nothing to do with fin efficacy, just experimenting).

in Progress Pictures 145 upvotes 4 years ago

The user experienced significant hair thickening after using topical minoxidil and oral finasteride for about 5 months and is considering switching from finasteride to RU58841. Other users encourage the original poster to continue the current treatment due to the positive results.

community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 2 years ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community 20M Losing/lost hope, have tried everything

in Chat 16 upvotes 1 month ago

A 20-year-old is experiencing hair loss and has tried oral and topical minoxidil, finasteride, and is considering dutasteride and a hair transplant. They feel frustrated and hopeless due to the lack of results and its effect on their mental health.

community 2025 Official beginner guide for “I’m losing my hair, what can I do?”

in General 816 upvotes 6 months ago

For hair loss, start with Finasteride, Minoxidil, Ketoconazole shampoo, and Microneedling. For severe cases, consider Dutasteride, oral Minoxidil, or hair transplants.

community Boys I am just a gonner. What on earth is my scalp even going through. Looks like world war 3. Pyril 3 months. Topical melitonin/progesterone/fin, dut, fin, oral min, laser trash, anus stimulation. Nothing. Donor area is decimated 😂.

in Progress Pictures 83 upvotes 2 years ago

Treating Seborrheic Dermatitis, a fungal scalp condition which can cause hair loss. Treatments discussed include antifungal shampoos, cold showers, exfoliating the scalp, taking Vitamin D, and stimulating the prostate through the anus.

community Hair much worse after 6 months?

in Progress Pictures 230 upvotes 1 year ago

A user experienced significant hair loss after 6 months of using 0.5mg finasteride daily. Suggestions from others included trying Dutasteride and Minoxidil, getting professional help from a dermatologist, and addressing high iron levels that could be contributing to the hair loss.

Related Research

3 / 3 results

research Pustular Dermatosis of the Scalp Due to Topical Minoxidil 5%

3 citations, January 2018

A woman had an unusual allergic reaction to a hair loss treatment, which cleared up after stopping the treatment and using a different medication.

research Effectivity of Minoxidil as a Treatment for Alopecia Areata

January 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)”

Minoxidil can effectively treat patchy hair loss by stimulating hair growth.

research Alopecia Areata Treated With Topical Minoxidil

16 citations, April 1984 in “Archives of Dermatology”

Topical minoxidil can help hair regrowth in alopecia areata patients, but maintaining the growth after stopping treatment is inconsistent.