Effects Of Keratin-Gelatin And Basic Fibroblast Growth Factor-Gelatin Composite Film On Open Wound Healing In Dogs And Cats
January 2007
TLDR Keratin-gelatin film improves wound healing in pets better than bFGF-gelatin.
The study investigated the effectiveness of keratin-gelatin and bFGF-gelatin composite films on wound healing in dogs and cats. Conducted on 36 dogs, the study found that keratin-gelatin composite film significantly improved wound healing, showing higher rates of epithelialization, wound contraction, and total healing compared to bFGF-gelatin. The keratin-gelatin film also facilitated early vascularization and acceptance of full-thickness skin mesh grafts, with 90-100% acceptance by Day 20 post-operation. Clinical cases involving 10 cats and 2 dogs confirmed its effectiveness. The study concluded that keratin-gelatin is a cost-effective biomaterial for wound healing, with potential commercial applications, though further research on different concentrations is recommended.