Diagnostic Value of the Diagonal Earlobe Crease in Combination with Lipoprotein(a) in Coronary Heart Disease
July 2025
in “
Scientific Reports
”
TLDR Diagonal earlobe crease and lipoprotein(a) together help diagnose coronary heart disease.
The study investigated the diagnostic value of diagonal earlobe crease (DELC) combined with lipoprotein(a) [Lp(a)] for coronary heart disease (CHD) in 862 patients with chest pain. Results indicated that both DELC and Lp(a) are positively correlated with CHD and serve as independent risk factors. The diagnostic model, which included age, sex, hypertension, diabetes mellitus, alopecia, DELC, triglycerides (TG), and Lp(a), showed a good fit with a Hosmer-Lemeshow test P-value of 0.683. The area under the curve (AUC) for DELC and Lp(a) was 0.729, demonstrating strong diagnostic value for CHD. The combination of DELC and Lp(a) is valuable for diagnosing CHD.