Diffuse Alopecia: Clinical, Trichoscopic, Histopathological and Immunohistochemical Challenges in the Diagnosis

Hair follicle counts and ratios are helpful in diagnosing hair loss types, but should be used with other specific features for accurate diagnosis.

Trichoscopy helped diagnose and treat a woman with two different types of hair loss.

Multiphoton microscopy can non-invasively tell apart scarring from non-scarring hair loss and could aid in treatment.

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Alopecia areata is a type of hair loss that can lead to complete baldness, often associated with other autoimmune conditions, and half of the cases may see hair return within a year.

Trichotillometry can measure hair plucking force, aiding alopecia treatment evaluation.

Detailed patient history and physical exams are crucial for diagnosing hair loss.

Minoxidil promotes hair growth but exact mechanism is unknown.