Diagnosis and Treatment of Staphylococcus Aureus Infections of the Skin and Mucous Membranes

    Helmut Schöfer, R Bruns, Isaak Effendy, Martin Hartmann, Uta Jappe, Andreas Plettenberg, Holger Reimann, Harald Seifert, Pramod M. Shah, Cord Sunderkötter, Tobias Weberschock, Thomas A. Wichelhaus, Alexander Nast
    TLDR Accurate diagnosis and combined antibiotic treatment are crucial for Staphylococcus aureus skin infections.
    The document reviewed the diagnosis and treatment of Staphylococcus aureus infections of the skin and mucous membranes, emphasizing the importance of accurate diagnosis due to the rise of antibiotic-resistant strains like MRSA. It recommended using a combination of topical and systemic antibiotics based on infection severity and type, and highlighted preventive measures such as nasal decolonization with mupirocin and proper hygiene. The review also discussed the unique superantigen activity of staphylococcal exfoliative toxins, the efficacy of topical agents like mupirocin and fusidic acid, and the need for ongoing research to update treatment protocols in response to emerging resistance patterns.
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