Developing Patient-Derived 3D-Bioprinting models of pancreatic cancer

    September 2024 in “ Journal of Advanced Research
    Hang Sun, Yan Wang, Minghao Sun, Xindi Ke, Changcan Li, Bao Jin, Mingchang Pang, Yanan Wang, Shangze Jiang, Liwei Du, Shunda Du, Shouxian Zhong, Haitao Zhao, Yuan Pang, Yongliang Sun, Zhiying Yang, Huayu Yang, Yilei Mao
    TLDR 3D-bioprinting models of pancreatic cancer could help personalize treatments but need more testing.
    The study on patient-derived 3D-bioprinting models of pancreatic cancer highlights their effectiveness as preclinical tools, as they maintain essential genomic and histological features. These models exhibit drug sensitivity profiles that may correlate with clinical outcomes, suggesting their potential in personalizing treatment strategies and forecasting patient prognoses. However, further validation with larger patient cohorts is necessary to confirm their clinical utility.
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