Dermatoporosis: A Further Step to Recognition

The document discussed dermatoporosis, a chronic skin fragility syndrome prevalent in the elderly, characterized by skin atrophy, senile purpura, and pseudoscars. A study by Humbert et al. suggested that topical vitamin C could reduce signs of dermatoporosis, indicating a potential link to vitamin C deficiency. Dermatoporosis was found to be common, with a prevalence of 32% to 37.5% in older populations. The condition was primarily due to aging and sun exposure, with secondary causes linked to corticosteroid use. The study highlighted the role of hyalurosome dysfunction and decreased CD44 and hyaluronate levels in skin fragility. Treatments focused on activating the hyalurosome platform using HA fragments and retinaldehyde to improve skin condition. The document suggested that vitamin C might be beneficial in topical products for preventing and reversing dermatoporosis.