Dermal Mucinosis in the Eosinophilia-Myalgia Syndrome

The document described a case of eosinophilia-myalgia syndrome (EMS) with an unusual presentation of cutaneous mucinosis in a 53-year-old woman who had used L-tryptophan. Although her eosinophil count was low, likely due to discontinuation of L-tryptophan, a skin biopsy confirmed the presence of abundant mucin in the dermis. This case was notable for the absence of a sclerodermalike syndrome, which is often associated with mucinosis. The findings led the authors to propose that EMS should be considered in the differential diagnosis when encountering dermal mucinosis and that EMS be recognized as a potential underlying condition for dermal mucinosis. The document was a single case report and did not involve a study with multiple participants.