The Demonstration of Cutaneous Nerves
November 1969
in “
Journal of Investigative Dermatology
”
Studysummary In this study, researchers standardized the Koelle and Friedenwald technique as modified by Gomori to reliably demonstrate discrete enzyme localization around eyebrow hair follicles in humans.
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The document discussed the successful standardization of a technique for demonstrating cutaneous nerves using cholinesterase staining, which allowed for clear and predictable localization of enzymes. This technique, as modified by Gomori, was applied to show nerves around a vellus hair follicle in the human eyebrow, highlighting the extent of the follicle end-organ with enzyme activity diffusion.