Clinical Evaluation of COVID-19 Survivors at a Public Multidisciplinary Health Clinic

August 2025 in “ Biomedicines ”

Ariele Barreto Haagsma, Felipe Giaretta Otto, Maria Leonor Gomes de Sá Vianna, Paula Muller Maingue, A Müller, Nayanne Hevelin dos Santos de Oliveira, Luísa Arcoverde Abbott, Felipe Paes Gomes da Silva, Carolline Konzen Klein, Denise Herzog, Julia Carolina Baldo Fantin Unruh, Lucas Schoeler, Dayane Mayumi Miyasaki, Jamil Faissal Soni, Rebecca Saray Marchesini Stival, Cristina Pellegrino Baena

hair loss post-acute COVID-19 syndrome PACS

TLDR Most COVID-19 survivors developed post-acute symptoms, especially if they had been in the ICU, but the severity of initial infection didn't predict these symptoms.

This study evaluated 113 COVID-19 survivors at a multidisciplinary clinic in Brazil to assess the association of sociodemographic factors and acute infection features with post-acute COVID-19 syndrome (PACS). It found that 63.71% of participants were diagnosed with PACS, with a median of 130 days post-symptom onset. Those with PACS were more likely to have been admitted to the ICU and experienced symptoms like hair loss (44.4% vs. 17.1%), lower limb paresthesia (34.7% vs. 9.8%), and slow thinking speed (28.2% vs. 0.0%) compared to those with subacute infection. However, the severity of the acute infection did not predict PACS; only the time since symptom onset was independently associated with a PACS diagnosis.

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