Comparıson of the effect of the autogenıc and xenogenıc use of platelet-rıch plasma on rabbıt chondrocutaneous composıte graft survıval

This study investigated the effects of autogenic and xenogenic platelet-rich plasma (PRP) on the viability of composite grafts in rabbits. Nine rabbits were used, with each ear divided into three groups receiving serum physiologic, autogenic PRP, or human-derived xenogenic PRP. After 3 weeks, evaluations showed that both autogenic and xenogenic PRP improved graft viability compared to the control group. Although autogenic PRP showed better graft viability and less necrosis macroscopically, the difference was not statistically significant. Histopathological analysis revealed significantly higher angiogenesis in the autogenic PRP group. The study concluded that while autogenic PRP had better histopathological results, xenogenic PRP could be a viable alternative for studies requiring macroscopic evaluation.