Comparison of Novel Hematological Biomarkers in Alopecia Areata and Other Non-Cicatricial Alopecia: A Retrospective Study

This retrospective study analyzed blood cell (BC) count and derived parameters in 170 patients with various types of not-cicatricial alopecia, including alopecia areata (AA), telogen effluvium (TE), and androgenic alopecia (AGA), as well as psoriasis and hidradenitis suppurativa (HS). The study found that BC-count and derived values were similar across the alopecia groups but differed from those in psoriasis and HS. TE showed an inflammatory profile closer to psoriasis. Significant findings included a reduction in red blood cells (RBCs) in severe versus patchy AA and an increase in the systemic immune-inflammation index (SII) in acute versus chronic AA. The study suggests that BC-count and derived parameters could be useful prognostic and therapeutic biomarkers in AA and TE.