Colonic Intussusception Due to a Large Ascending Colon Lipoma

This case report described a 74-year-old man who experienced colonic intussusception due to a large lipoma in the ascending colon. Initially presenting with abdominal pain and constipation, a colonoscopy revealed a large lipoma near the ileocecal valve. Four months later, the patient developed intussusception, confirmed by a CT scan, and underwent an emergency right hemicolectomy. The pathology confirmed a 6-cm lipoma with ischemic changes. Colonic lipomas, though often asymptomatic, can lead to complications like intussusception. They are the most common submucosal tumors in the colon, with an incidence rate of 0.2-0.8%, and are typically found in the ascending colon. Endoscopic removal should be approached cautiously due to potential complications.