Clinical and Hematological Studies on Experimentally Induced Selenosis in Crossbred Cow Calves

The study investigated the effects of sodium selenite-induced subacute and chronic selenosis on clinical and haematological parameters in cross-bred cow calves. Subacute selenosis was induced with a dose of 2.5 mg/kg for 21 days, resulting in symptoms like anorexia, salivation, joint swelling, and labored breathing. Chronic selenosis was induced with 0.25 mg/kg for 16 weeks, leading to rough hair coat, alopecia, and hoof enlargement. Both forms of selenosis significantly affected blood parameters such as haemoglobin, packed cell volume, and total erythrocyte and leukocyte counts, with chronic toxicity also altering mean corpuscular volume and haemoglobin. Erythrocyte sedimentation rate and mean corpuscular haemoglobin concentration were not significantly affected.