A Case of Acrodermatitis Enteropathica
January 2016
in “
Journal of clinical & experimental dermatology research
”
Studysummary This case report describes a child with acrodermatitis enteropathica showing dramatic improvement with oral zinc therapy, highlighting the importance of early diagnosis and treatment to prevent severe outcomes.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
Acrodermatitis enteropathica (AE) is a rare, potentially fatal skin condition that can be either inherited or acquired, with both forms affecting males and females equally. It is characterized by a triad of symptoms: dermatitis around body openings and extremities, diarrhea, and alopecia. The skin lesions are distinctive and can progress to more severe forms. The condition responds well to oral zinc therapy. This case report highlights the importance of considering AE in the differential diagnosis of pediatric blistering skin disorders, especially as symptoms can mimic other diseases. Early diagnosis and treatment are crucial to reduce mortality and prevent the complications of zinc deficiency. The report also notes that the disease often presents when infants transition from breast milk, which is high in zinc, to other foods with lower zinc content and absorbability.