Association Between Coronary Artery Disease and Diagonal Earlobe and Preauricular Creases in Men

This study on 110 male patients found a significant association between coronary artery disease (CAD) and the presence of bilateral diagonal earlobe crease (ELC) and preauricular crease (PAC). Patients with CAD had a higher prevalence of ELC (60% vs. 30%) and PAC (87.5% vs. 53.3%) compared to controls, with odds ratios of 3.1 and 5.5, respectively. The presence of both creases had a high positive predictive value of 90% for CAD, suggesting their potential as non-invasive indicators of CAD risk. However, androgenetic alopecia and thoracic hairiness were not associated with CAD. Further research was recommended to explore these findings' implications on mortality and atherosclerotic disease in other organs.