Association of DNA damage with vitamin D and hair heavy metals of obese women

The study with 134 women aged 20 to 50 years found that 96.3% had vitamin D deficiency and there was no significant difference in serum 25(OH)D levels, DNA damage indicators, hair heavy metal concentrations, and dietary nutrients between obese and non-obese groups. However, in obese women, higher serum 25(OH)D levels (≥31 nmol/L) were associated with less DNA damage, while higher hair chromium concentrations (≥5.88 mg/kg) were associated with more DNA damage. The study suggests that adequate vitamin D levels might reduce, and high chromium levels might increase DNA damage in obese individuals, although causal relationships could not be established.