Androgenetic Alopecia
December 2007
Studysummary This article reviews the causes and pattern of androgenetic alopecia and reports no new research findings.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
Androgenetic alopecia (AGA) is the most common form of hair loss, affecting a large percentage of both men and women. It is characterized by a progressive reduction in the diameter, length, and pigmentation of the hair, primarily in the frontal, temporal, and vertex areas of the scalp. This hair thinning is caused by the effects of dihydrotestosterone (DHT), a testosterone metabolite, on androgen-sensitive hair follicles. The sensitivity to androgens is determined by genetics and is influenced by the production of DHT through the enzyme 5α-reductase.
