Alopecia Induced by Lopinavir Plus Ritonavir Therapy in an HIV Patient

    July 2007 in “ PubMed ”
    George Chrysos, Sotirios Mikros, Stelios Kokkoris, Androula Pastelli, George Kontochristopoulos
    TLDR An HIV patient's complete hair loss was reversed after switching from lopinavir/ritonavir to nelfinavir.
    A 62-year-old HIV patient experienced alopecia totalis of the scalp, eyebrows, and eyelashes 18 months after starting antiretroviral therapy with lopinavir/ritonavir, efavirenz, and stavudine. The alopecia reversed completely within 2 months after substituting nelfinavir for lopinavir/ritonavir, with no other changes in treatment. This case was notable as it was the second reported instance of lopinavir/ritonavir-associated alopecia totalis in the international literature.
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