The Review On Alopecia Areata: A Comprehensive Review Of Pathogenesis, Diagnosis, Clinical Pattern And Remedies
December 2025
in “
Zenodo (CERN European Organization for Nuclear Research)
”
TLDR Alopecia areata causes sudden, patchy hair loss due to immune system attacks on hair follicles.
Alopecia Areata (AA) is a chronic, immune-mediated disorder resulting in non-scarring hair loss, typically presenting as sudden, patchy baldness on the scalp and other hair-bearing areas. It is caused by an immunological attack on hair follicles, often in genetically predisposed individuals. The condition can affect both males and females equally and is most common in childhood or early adulthood. The pathogenesis involves a complex interplay of immunological dysregulation, environmental stressors, and genetic factors, with T-cell-mediated inflammation playing a significant role. Alopecia areata is characterized by localized hair loss, while alopecia totalis involves complete scalp or body hair loss.