Alopecia Areata: A Study of 736 Cases at the Mayo Clinic

Alopecia areata, a condition characterized by isolated, asymptomatic hair loss from circumscribed plaques, often on the scalp, can progress to total hair loss (alopecia totalis). A study of 736 cases at the Mayo Clinic found that severe cases often begin at an average age of 22.9 years and are permanent in 30% of cases. Emotional stress and psychiatric conditions were noted as contributing factors in some cases. Treatment remains unsatisfactory, with corticosteroids providing temporary relief but not preventing relapse. The study also suggested a link between alopecia areata and hypersensitivity diseases, such as atopic dermatitis and autoimmune disorders, warranting further investigation.