Allelic frequencies for the seventeen Y-STR loci observed in Iraqi male patients with prostate cancer

The study investigated allelic frequencies of 17 Y-chromosome short tandem repeat loci in 100 Iraqi male patients with prostate cancer and normal controls to evaluate their association with the disease. It found that males with allele 10 of DYS391 or allele 13 of DYS393 had a higher incidence of prostate cancer, suggesting these alleles may increase susceptibility. Conversely, alleles 9 and 14 of DYS439 or allele 15 of DYS385b appeared to confer resistance. The findings indicated that these genetic markers could potentially be used for screening and predicting prostate cancer susceptibility in the Iraqi population.