Adenolipoma—Eccrine and Apocrine Variants With Evidence for a Hamartomatous Process

The study reviewed 11 cases of adenolipoma, confirming previous findings and adding new observations. The patients, aged 53 on average, included 6 men and 5 women. The lesions varied, with some presenting as nevus lipomatosus and others as spindle cell lipomas, each showing eccrine/apocrine glandular components. The study suggested these lesions might develop from peripheral adipose tissue of eccrine glands or result from gland entrapment by adipose proliferation. The findings supported the concept of a hamartomatous process, particularly in a unique apocrine variant not previously described. The study highlighted the complexity and heterogeneity of lipogenic lesions, emphasizing the role of cytogenetics in understanding their pathogenesis.