The Complex Detection of ABO-System Antigens and Keratin Polymorphism in the Forensic Medical Study of Hair

    June 1997 in “ PubMed
    Iu V Kukhar'kov, G F Puchkov, S R Borovko
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    Studysummary This study found that both AB(0) antigens and keratin phenotype can be determined from the same hair fragment using specific protein extraction and analysis methods. Our plain-language summary of this paper — not a Tressless recommendation.
    The study explored the forensic application of detecting AB(O)-system antigens and keratin polymorphism in hair. Researchers extracted hair proteins using a specific buffer and analyzed them through gradient polyacrylamide gel electrophoresis. They demonstrated that a single 5 cm hair, previously analyzed for AB0 blood group using the absorption-elution test, was sufficient to assess the keratin phenotype. This method allowed for the simultaneous determination of AB(0) antigens and keratin phenotype in the same hair fragments, providing a valuable tool for forensic investigations.
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