A Replication Study Confirmed the EDAR Gene to Be a Major Contributor to Population Differentiation Regarding Head Hair Thickness in Asia
August 2008
in “
Human genetics
”
![Image of study](/images/research/410e935e-8f45-409d-b74a-6473e4821c05/medium/29411.jpg)
TLDR The EDAR gene greatly affects hair thickness in Asian populations.
In a study examining the genetic basis of hair thickness variation among Asian populations, researchers found that a single nucleotide polymorphism (SNP) in the ectodysplasin A receptor gene (EDAR 1540T/C) was significantly associated with hair fiber thickness in a Japanese population, confirming previous findings in Thai-Mai and Indonesian groups. The association was highly significant (P = 2.7 × 10−6) in the Japanese sample and even stronger (P = 3.8 × 10−10) when data from all three populations were combined, surpassing the influence of age, sex, and population differences. These results suggest that the EDAR gene plays a major role in determining hair thickness among various Asian populations.
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2 / results![Enhanced Ectodysplasin-A Receptor Signaling Alters Multiple Fiber Characteristics to Produce the East Asian Hair Form](/images/research/f3ac5424-c101-4e27-8b74-e6c280e57d75/small/29408.jpg)
research Enhanced Ectodysplasin-A Receptor Signaling Alters Multiple Fiber Characteristics to Produce the East Asian Hair Form
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