A Pilot Study of a Grape Seed Procyanidin Extract for Lung Cancer Chemoprevention

    May 2019 in “Cancer Prevention Research”
    Jenny T. Mao, Qingyi Lu, Bingye Xue, Patricia Neis, Félix Zamora, Laurie Lundmark, Clifford Qualls, Larry Massie
    Image of study
    TLDR Grape seed extract may safely and effectively help prevent lung cancer.
    This pilot study tested the safety and efficacy of a grape seed procyanidin extract (LP) for lung cancer chemoprevention. Six subjects completed the 3-month treatment course and reported no adverse effects. LP treatment decreased bronchial epithelial cell proliferation by 55% and downregulated serum oncomirs miR-19a, -19b, and -106b. LP treatment also significantly reduced bronchial histopathology grading, although the clinical significance of this is unclear. The study suggests that LP may be a safe and effective agent for lung cancer chemoprevention.
    View this study on aacrjournals.org →