Epidermal Growth Factor Receptor Inhibitors: Cutaneous Side Effects and Their Management
September 2017
in “
PubMed
”
Studysummary This article discusses the common cutaneous side effects associated with EGFR inhibitors, emphasizing the importance of their management due to potential impacts on patients' quality of life and therapy response; no new empirical findings are reported.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
Epidermal growth factor receptor (EGFR) inhibitors were a class of targeted anticancer therapies that aimed to interfere with specific pathways involved in cancer cell proliferation. Despite being less severe than traditional chemotherapy, these inhibitors often caused significant cutaneous side effects due to the expression of EGFR in epithelial tissues, including the skin and hair follicles. These side effects could impact patients' quality of life but were sometimes linked to a better therapeutic response. It was crucial for clinicians to understand and manage these dermatologic toxicities effectively.
