Delayed Telogen Replacement in a Boy's Scalp

    January 1998 in “ Dermatology
    Marcella Guarrera, Carla Cipriani, Alfredo Rebora
    Studysummary This study observed that vellus hairs and empty spaces are present in prepubertal children's scalps, but they likely do not indicate androgenetic alopecia, suggesting a natural 'true resting' phase of scalp hair.
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    The study investigated delayed telogen replacement in an 8-year-old boy's scalp over a period from July 1996 to May 1997 using the phototrichogram technique on 60 hairs. It found that 52% of the hairs were terminal anagen hairs, while 22% followed a regular hair cycle. Vellus hairs and empty spaces were observed in 18% and 8% of follicles, respectively, with 2% showing both. The presence of vellus hairs and empty spaces in children, without the influence of gonadal androgens or 5α-reductase, suggested that these might not indicate androgenetic alopecia (AGA) but rather a physiological resting phase of some scalp hair. The study concluded that androgens might exacerbate this phenomenon, potentially contributing to AGA development.
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