Case Report: Biological Therapy Association, Case Report of a Patient with Ankylosing Spondylitis and Alopecia Areata

    January 2024
    Melina Pinheiro Conscetta, Laís Roberta Garcia Bernardini Venâncio
    From the encyclopedia
    Alopecia Areata →

    autoimmune disorder causing patchy hair loss

    Baricitinib →

    JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

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    Studysummary In this case report, a patient with ankylosing spondylitis and alopecia areata who used a combination of baricitinib and golimumab experienced hair regrowth without adverse effects, but the efficacy of this treatment combination remains unestablished according to the researchers.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    This case report discusses a patient with ankylosing spondylitis who developed alopecia areata after severe emotional stress while on biological therapy with golimumab. Despite using various corticosteroids, the patient's hair loss did not improve. A decision was made to combine baricitinib with golimumab, and after 8 months, hair regrowth was observed. There is currently no standard recommendation for this combination therapy in treating ankylosing spondylitis with alopecia areata, but the patient has experienced no adverse effects so far.
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