Wound-Induced Hair Follicle Neogenesis as a Promising Approach for Hair Regeneration
August 2023
in “Molecules and Cells”
TLDR Hair can regrow after significant damage through a process similar to how it forms before birth, involving stem cells and various cell types and signals. This could be a new way to prevent scarring and promote hair growth.
The review discusses the process of Wound-Induced Hair Follicle Neogenesis (WIHN), a mechanism that allows hair follicles to regenerate after large-scale wounding in several adult mammals. This process is similar to embryonic hair follicle development. The study highlights the role of stem cells that transform into neogenic hair follicles in response to wounding. It also emphasizes the importance of immune cells, mesenchymal cells, and various signaling pathways in this process. WIHN is seen as a promising therapeutic approach for promoting hair follicle regeneration and preventing scar formation by reprogramming cellular states. The review investigates the contribution of different cell types and molecular mechanisms to WIHN.
View this study on molcells.org →
Related
research Wound-Induced Hair Follicle Neogenesis as a Promising Approach for Hair Regeneration
Hair can regrow after significant damage through a process similar to how it forms before birth, involving stem cells and various cell types and signals. This could be a new way to prevent scarring and promote hair growth.
research Hair Follicle Morphogenesis During Embryogenesis, Neogenesis, and Organogenesis
The document concludes that understanding adult stem cells and their environments can help improve skin regeneration in the future.
research Wound Induced Hair Neogenesis – A Novel Paradigm for Studying Regeneration and Aging
Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.
research Through the lens of hair follicle neogenesis, a new focus on mechanisms of skin regeneration after wounding
Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.
research [Wound-induced hair follicle neogenesis: a new perspective on hair follicles regeneration in adult mammals].
Wound-induced hair follicle creation is a complex process in adult mammals that involves various cells and immune responses, and understanding it better could help improve skin healing strategies.