Use of urinary bladder matrix, a bioactive, acellular scaffold along with platelet rich plasma (PRP) in transplant donor scars and androgenetic alopecia: 5-year experience in hair duplication and hair loss prevention/non-surgical restoration

Nine years ago, a study was conducted on the use of urinary bladder matrix (UBM), a bioactive, acellular scaffold, in conjunction with platelet-rich plasma (PRP) for the treatment of transplant donor scars and androgenetic alopecia. The UBM, derived from the urinary bladder and known as MatriStem-Acell, is an FDA-approved resorbable bio-scaffold material that has been used successfully in various medical procedures. The study found significant anecdotal support for the benefits of UBM regenerative technology in hair restoration and hair loss prevention. It was suggested that UBM functions to recruit and signal local and circulating stem cells that may then initiate/promote folliculogenesis, the formation of new hair follicles. The combination of ACell/Enhanced PRP was found to be effective in rescuing damaged or miniaturizing hairs and causing hair duplication.