Spotlight in Plastic Surgery: October 2022

    September 2022 in “Plastic and Reconstructive Surgery”
    Brett T. Phillips, Mario Alessandri‐Bonetti, Murad J. Karadsheh, Aneesh Karir, Siddharth Mendiratta, Kerry A. Morrison, Miguel Ribeiro Matias, Tyler Safran, Benjamin R. Slavin, Yoshiko Toyoda, Otto R Ziegler Rodríguez, Arun K. Gosain
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    TLDR Baricitinib helps with severe hair loss, negative-pressure therapy lowers hernia recurrence, tranexamic acid reduces bleeding, robot-assisted breast surgery may improve outcomes, and acellular dermal matrix could decrease breast reconstruction complications.
    The "Spotlight in Plastic Surgery: October 2022" review discusses several studies related to plastic surgery. A study involving 1200 patients found that baricitinib, an oral JAK1 and JAK2 inhibitor, was more effective than a placebo in treating severe alopecia areata, suggesting its potential for hair restoration treatments. Another study with 114 patients showed that negative-pressure wound therapy reduced hernia recurrence rates in patients having ventral hernia repair with panniculectomy. A study of 9535 patients demonstrated that tranexamic acid safely reduced bleeding in noncardiac surgery, supporting its growing use in plastic surgery procedures. A retrospective review of 73 women indicated that robot-assisted nipple-sparing mastectomy and reconstruction could increasingly replace traditional open surgery due to better cosmetic outcomes and similar complication rates. Finally, a study of over 9500 patients found that long-term acellular dermal matrix might be linked with less capsular contracture and fewer implant complications in breast reconstruction.
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